Abdollah Khosravanian - Chemical and Petroleum Engineering Department, Sharif University of Technology, Tehran ۱۱۱۵۵‐۸۶۳۹, Iran
Ahmad Moslehipour - Farabi Research Center, Jam, Bushehr, Iran
Hossein Ashrafian - Department of Chemistry and Biochemistry, the Ohio State University, Columbus, OH, USA

Graphene quantum dots (GQDs), which are the most capable carbon-based nanostructures, play a significant role in biological studies. These nanostructures show significant attributes including low toxicity, high solubility in numerous solvents, notable electronic characteristics, strong chemical inertness, high specific surface areas, and abundant sites for functionalization. In addition, GQDs have adaptability as well as capability to be improved via absorbent surface chemicals as well as the addition of modifiers or nanoparticles. Accordingly, we have presented here the fundamental properties, synthesis techniques, and the applications of GQDs in biosensing, bioimaging, and drug delivery. It is worth mentioning that toxicity is a significant issue which has restricted biological applications of QDs. Hence, the toxicological features of GQDs have been covered in this review paper.

Graphene quantum dots, Nanotechnology, Drug Delivery, bioimaging, Biosensing