Optimization of beamline diameter in spot scanning proton therapy for minimization of secondary particles using finite element method
عنوان مقاله: Optimization of beamline diameter in spot scanning proton therapy for minimization of secondary particles using finite element method
شناسه ملی مقاله: JR_RPE-1-3_002
منتشر شده در در سال 1399
شناسه ملی مقاله: JR_RPE-1-3_002
منتشر شده در در سال 1399
مشخصات نویسندگان مقاله:
Amir Veiskarami - Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
Mahdi Sadeghi - Iran University of Medical Sciences, Medical Physics Department, Tehran, Iran
Dariush Sardari - Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
Shahryar Malekie - Radiation Application Research School, Nuclear Science & Technology Research Institute, PO Box ۳۱۴۸۵-۴۹۸, Karaj, Iran
خلاصه مقاله:
Amir Veiskarami - Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
Mahdi Sadeghi - Iran University of Medical Sciences, Medical Physics Department, Tehran, Iran
Dariush Sardari - Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
Shahryar Malekie - Radiation Application Research School, Nuclear Science & Technology Research Institute, PO Box ۳۱۴۸۵-۴۹۸, Karaj, Iran
Collision of protons with background gas and beamline wall in proton therapy causes the creation of secondary particles, e.g. neutrons, which results in more difficulties in curing the tumors. In the present simulation-based study, the optimum diameter of proton beamline was determined to minimize the production of secondary particles in the presence of electric field with the magnitude of 50 kV/m, perpendicular equal magnetic fields of 0.7 T, and background gas of argon under Bounce boundary conditions via finite element method. The results showed that the optimum diameter of the beamline for minimization of the secondary particles in the spot scanning proton therapy in the aforementioned conditions was 7 mm. Also, the values of drift velocities of protons were plotted in different time steps of 10 ns to 50 ns for the optimized size of the beamline. Due to few interactions of forwarding particles with background gas, the results showed that the forwarding particles in the propagation direction have greater velocities than those of rear particles. The results can be used in spot scanning proton therapy for curing the localized cancers.
کلمات کلیدی: Spot Scanning Proton Therapy, Beamline Diameter, Secondary Particles, Finite Element Method
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1142030/