Mohammad Biglari - Department of Chemistry, College of Science, University of Guilan, University Campus ۲, Rasht, Iran
Farhad Shirini - Department of Chemistry, College of Science, University of Guilan, University Campus ,۲ Rasht, Iran Department of Chemistry, College of Science, University of Guilan, Rasht, ۴۱۳۳۵-۱۹۱۴۱, Iran
Nosratollah Mahmoodi - Department of Chemistry, College of Science, University of Guilan, University Campus ,۲ Rasht, Iran Department of Chemistry, College of Science, University of Guilan, Rasht, ۴۱۳۳۵-۱۹۱۴۱, Iran
Meysam Alipour Khoshdel - Department of Chemistry, College of Science, University of Guilan, University Campus ۲, Rasht, Iran
Mehdi Zabihzadeh - Department of Chemistry, College of Science, University of Guilan, University Campus ۲, Rasht, Iran
Mohaddeseh Safarpoor Nikoo Langarudi - Department of Chemistry, College of Science, University of Guilan, University Campus ۲, Rasht, Iran

Recently, research on deep eutectic solvents (DESs) as a new generation of eco-friendly solvent/catalyst systems has attracted strong interest in organic synthesis. DES consists out of two or three components which combine via hydrogen bond interactions to form eutectic mixtures, characterised by a melting point lower than that of each individual component. 1, 2Quinazolinone derivatives are important class of heterocyclic compounds with various applications in pharmaceutical industries.3 Hence, design and development of novel synthetic methods to the synthesis of the libraries of these compounds is an interesting field for many organic chemists. As a part of our continuing interest on designing environmentally benign methods for various chemical transformations, herein we have described an efficient and more practical route for the synthesis of triazolo[2,1‑b]quinazolinones using modified ChCl based DES as a green catalyst. All reactions are performed during acceptable time with high efficiency

Multicomponent reactions, Choline chloride, Deep eutectic solvents, Triazolo[2,1‑b]quinazolinones, Green organic synthesis.