Andreia Henriques - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Regina Arantes-Rodrigues - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Ana I Faustino-Rocha - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Catarina I Teixeira-Guedes - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Jacinta Pinho-Oliveira - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Daniela Talhada - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
José H Teixeira - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Andreia Andrade - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Bruno Colaço - Department of Zootechnics, University of Trás-os-Montes and Alto Douro, ۹۱۱ Vila Real, Portugal Center for the Study of Animal Sciences (CECA), University of Porto, ۴۴۸۵-۶۶۱, Porto, PortugalCentre for the Research and Technology
Maria N Paiva-Cardoso - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal
Maria J Pires - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, ۴۴۸۵-۶۶۱, Porto, PortugalCentre for the Research and
Ana MVD Ferreira - Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۸۰۱, Vila Real, Portugal
Fernando M Nunes - Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۸۰۱, Vila Real, Portugal
Paula A Oliveira - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, ۴۴۸۵-۶۶۱, Porto, PortugalCentre for the Research and

Objective(s):Green tea (GT) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials and Methods: The GT characterization was performed using spectrophotometric methods. Urinary bladder lesions were induced using N-butyl-N-(۴-hydroxybutyl) nitrosamine (BBN) by gavage during ۱۰ weeks and whole GT (۰.۵%) was provided ad libitum during ۲۰ weeks. Results:Animals from groups BBN+GT and BBN only developed preneoplastic lesions. Conclusion:We did not observe any effects by GT infusion administration on urinary bladder cancer development.

green tea, Mice, N-butyl-N-(۴-hydroxybutyl)nitro- samine, Urinary bladder cancer