Zahra Dashtizadeh - Master of Science, Department of Chemistry, Payame Noor University, Mashhad. Iran,
Abdolrasoul H. Ebrahimabadi - Associate Professor, Essential Oils Research Institute, University of Kashan, Kashan. Iran,
Azam Monfared - Associate Professor, Department of chemistry, Payame Noor University, Tehran. Iran,
Sayed Ahmad Mirshokraei - Professor, Department of chemistry, Payame Noor University, Tehran. Iran,
Samaneh Heydari - PhD student, Department of Chemistry, Mohaghegh Ardabili University, Ardabil. Iran,

In antioxidant activities, by DPPH test, IC۵۰ values ۶۳.۱۱±۱.۴۵, ۱۰۲.۸۱±۱.۰۸, ۲۰۱.۲۴±۲.۱۸ and ۱۳۱.۶۲±۰.۴۶ μg/ml were obtained for leaf, flower, stem and seed extract respectively, comparable to that of BHT (IC۵۰ = ۱۹.۷۲± ۰.۸۰ μg/ml). In beta-carotene-linolenic acid test, inhibition percentages of %۵۷.۲۲, %۴۸.۷۴, %۴۸.۴۸ and %۴۴.۸۵ were recorded for leaf, flower, stem and seed extracts, respectively, comparable to that of BHT (%۸۹.۴۳). In total phenolic compounds contents of the extracts equivalent to galic acid were evaluated ۶۸.۸۲, ۳۰.۲۵, ۱۶.۷۶ and ۲۷.۸۶ μg/mg for leaf, flower, stem and seed extracts,respectively.In antimicrobial activity by disk diffusion method, leaf extract, inhibited paratyphoid microbe with a ۱۲ mm corona by at least ۶۰.۲۵μg/ml dilution, stem extract inhibited pneumonia microbe by ۱۸ mm corona at least ۵۰۰μg/ml dilution and flower extract inhibited two before microbes with a ۱۲ and ۱۳mm coronas by at least ۵۰۰ and ۲۵۰μg/ml dilutions respectively.

Echium italicum L., Boriginaceae; Extract; Antioxidant activity; DPPH assay, Folin-Ciocalteu test; Beta-carotene test; Antimicrobial activity; Disk diffusion method; Micro-broth dilution.