Mohammadreza Abdollahzadeh Estakhri - Sina Hospital, Tehran University of Medical Science, Tehran, Iran.
Parviz Kavakeb - Sina Hospital, Tehran University of Medical Science, Tehran, Iran.
Delaram Fathi - Department of Technical and Vocational Organization, Karaj University, Karaj, Iran
Gholamreza Karimi - Faculty of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran
Amirhosein Mohammadpour - Faculty of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran
Maryam Rahbar - Sina Hospital, Tehran University of Medical Science, Tehran, Iran.

Background and Objective: Beta-۲ Microglobulin (β۲M) is a middle molecular weight uremic toxin. Lack of β۲M removal leads to β۲M accumulation and amyloidosis in hemodialysis patients. The present research aims to determine the relationship between β۲M and inflammatory factors, such as C-reactive protein (CRP), albumin, and high-density lipoprotein (HDL) in hemodialysis patients.  Methods: Fifty-four hemodialysis patients were selected and their pre- and post-dialysis serum levels of β۲M, CRP, albumin, and HDL, were measured. Results: There was an obvious inverse relationship between β۲M level and serum level of albumin, while no relationship was found between β۲M and CRP or HDL. Conclusion: According to the findings of this study, it was identified that inflammatory-induced increase in β۲M level in dialysis patients leads to reduced serum albumin

Beta-۲ Microglobulin, albumin, hemodialysis, inflammation.