SayedAlireza Mousavi - Department of Biology, School of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, Iran
Fatemeh Karami - Department of Medical Genetics, Applied Biophotonics Research Center, Science and Research Branch, Islamic Azad University, Tehran, Iran

Recently, Physical Activity has seized greatattention in decreasing the risk of canceramong high risk genetic alterations carriers.Owing to the extensive investigations onbreast cancer, it was aimed to review the roleof physical activity in modulating the risk ofbreast cancer among gene mutation carriers.We explored the internet in Google Scholar,Pubmed, Pubmed Central and Bing searchengines using main key words includingBreast cancer risk, high risk mutation,disease onset and physical activity. All themanuscripts after ۲۰۱۰ were included in thepresent review.

Physical activity, High risk, Mutationcarriers, Breast cancer