Electrochemical Determination of Mesalazine by Modified Graphite Paste Electrode with Poly (Benzoquinone) Chromium(III) Complex
عنوان مقاله: Electrochemical Determination of Mesalazine by Modified Graphite Paste Electrode with Poly (Benzoquinone) Chromium(III) Complex
شناسه ملی مقاله: JR_ANALCH-5-2_014
منتشر شده در در سال 1397
شناسه ملی مقاله: JR_ANALCH-5-2_014
منتشر شده در در سال 1397
مشخصات نویسندگان مقاله:
Arezo Nouri - Analytical Research Laboratory, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, P. O. Box: ۹۸۱۳۵-۶۷۴, Iran
Meissam Noroozifar - Analytical Research Laboratory, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, P. O. Box: ۹۸۱۳۵-۶۷۴, Iran
خلاصه مقاله:
Arezo Nouri - Analytical Research Laboratory, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, P. O. Box: ۹۸۱۳۵-۶۷۴, Iran
Meissam Noroozifar - Analytical Research Laboratory, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, P. O. Box: ۹۸۱۳۵-۶۷۴, Iran
In this work, for the first time poly (benzoquinone) chromium (III) complex (PBQC) was synthesized with a one pot, one step, simple and fast method. This novel polymer was used for modification of graphite paste electrode for electrochemical determination of Mesalazine. Moreover, this novel modifier was characterized by Fourier transform infrared spectroscopy, Field emission scanning electron microscopy, Energy-dispersive X-ray spectroscopy, Electrochemical impedance spectroscopy and electrochemistry methods such as cyclic voltammetry and differential pulse voltammetry. Various parameters which affect the electroanalytical application of this modified electrode were optimized and under the optimum condition, the calibration curve was linear in a wide range from ۲ to ۶۰۰ µM with a detection limit (S/N=۳) of ۷۰ nM. The proposed modified electrode is a good candidate for the determination of Mesalazine with satisfactory results in comparison with the other literature. Moreover, the proposed modified electrode, GPE/PBQC, was successfully used for determination of Mesalazine in pharmaceutical tablets.
کلمات کلیدی: Poly (benzoquinone) chromium(III) complex, Mesalazine, Modified graphite paste electrode, Pharmaceutical tablets
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1598300/