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Synthesis, characterization and antibacterial activities of new substituted (۱,۳)oxazepine ۱,۵-diones

عنوان مقاله: Synthesis, characterization and antibacterial activities of new substituted (۱,۳)oxazepine ۱,۵-diones
شناسه ملی مقاله: JR_IJNC-10-2_004
منتشر شده در در سال 1402
مشخصات نویسندگان مقاله:

mohammed ghanam - The General Directorate of Anbar Education / Ministry of Education / Anbar / Ramadi
Omar Mahdi - The General Directorate of Anbar Education / Ministry of Education / Anbar / Ramadi

خلاصه مقاله:
Novel Imine were prepared via the reaction of (p-chloro and p-methyl)aniline with (p-nitro and p-methoxy) benzaldehyde and later engaged in a condensation reaction with ۲-O-Acetylmalic anhydride in a dioxane as a solvent. The resulting products were found to be ۱,۳-oxazepine-۱,۵-diones and their derivatives. FT-IR , ۱HNMR and C.H.N. spectra were used to confirm the structures of products. The antibacterial properties of these compounds were also examined. In this work, the new substituted ۱,۳- oxazepine-۴,۷-dione derivatives were prepared successfully by using various substituted Schiff's bases . The ۱,۳-oxazepines has been evidenced by spectral analysis. The substances' antibacterial efficacy against several types of bacteria was assessed, and they shown similar activity to that of conventional medications.Novel Imine were prepared via the reaction of (p-chloro and p-methyl)aniline with (p-nitro and p-methoxy) benzaldehyde and later engaged in a condensation reaction with ۲-O-Acetylmalic anhydride in a dioxane as a solvent. The resulting products were found to be ۱,۳-oxazepine-۱,۵-diones and their derivatives. FT-IR , ۱HNMR and C.H.N. spectra were used to confirm the structures of products. The antibacterial properties of these compounds were also examined

کلمات کلیدی:
Antibacterial activities, ۱, ۳-oxazepine, Imine (Schiff' s Bases)

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1746910/