H. Kiani - Bioprocessing and Biodetection Lab, Department of Food Science, Technology and Engineering, University of Tehran, Islamic Republic of Iran.
M. Hojjatoleslamy - Department of Food Science and Technology, College of Agriculture, Islamic Azad University, Shahre Kord Branch, Shahre Kord, Islamic Republic of Iran.
S. M. Mousavi - Bioprocessing and Biodetection Lab, Department of Food Science, Technology and Engineering, University of Tehran, Islamic Republic of Iran.

In this work, Response Surface Methodology (RSM) and Artificial Neural Networks (ANN) were employed for the data reduction of a numerically simulated extraction process of sugar in an industrial RT۲ extractor. The numerical model developed in OpenFOAM library was first validated using actual plant data and its stability and sensitivity to the processing variables was tested. Then, the model was used to generate data of juice and pulp sugar concentrations as affected by the main processing parameters including draft, Silin number, and capacity. The data were modelled using RSM and ANN. Both RSM and ANN were able to predict the data accurately, however, R۲ values obtained for ANN were slightly higher. Since the numerical model can be time consuming to be solved for all data ranges, the regression equation obtained by the RSM method or the network created according to the ANN model can be utilized as fast and ready to use tools to optimize the extractor.

ANN, CFD, mass transfer, Open FOAM, RSM