Olayinka Oluseyi Ajao - Medical-Surgical Nursing Unit, Department of Nursing Science, Osun State University, Nigeria
Olamide Olajumoke Afolalu - Mental Health Nursing Unit, Department of Nursing Science, Osun State University, Nigeria
Ganiyat Adeniran - Maternal and Child Health Nursing Unit, Department of Nursing Science, Osun State University, Nigeria
Stephen Gbadebo Olawale - Community Health Nursing Unit, Department of Nursing Science, Osun State University, Nigeria
Rukayat Agboola-Bello - Maternal and Child Health Nursing Unit, Department of Nursing Science, Osun State University, Nigeria

Olayinka Oluseyi Ajao , Olamide Olajumoke Afolalu , Ganiyat Adeniran , Stephen Gbadebo Olawale , Rukayat Agboola-Bello  Background: Antiretroviral therapy (ART) has played a crucial role in minimizing the worldwide impact of HIV infection. Numerous HIV patients face challenges in adhering to their treatment due to various physical, social, and psychological factors. This study aimed to explore the correlation between psychosocial stress and treatment adherence among HIV/AIDS patients at a hospital in Nigeria. Methods: In this study, a descriptive analytical design was utilized to select (n=۱۷۱) HIV-infected clients attending the virology clinic at Uniosun Teaching Hospital (UTH). Convenient sampling was employed to choose participants from a total monthly population of ۲۷۱ patients who visit the clinic. Data collection was performed using a questionnaire consisting of four sections and ۵۷ items. Descriptive and inferential statistics, such as the Chi-square test and correlation analysis, were employed to present and analyze the data. Results: A significant proportion (۶۱.۴%) of the patients experienced a moderate level of stress. The most notable sources of stress reported by patients were the need for HIV status disclosure (۷۱.۹%) and rejection from family and friends (۶۶.۷%). Rejections by friends and family, stigma and discrimination, social and economic challenges, as well as antiretroviral therapy showed a significant association with HIV-related stress (p < ۰.۰۰۱). Furthermore, a significant inverse correlation was found between psychosocial stress and treatment adherence (r = -۰.۷۰۵, p < ۰.۰۰۱). Conclusion: Individuals living with HIV/AIDS (PLWHA) face significant levels of stress and often encounter rejection and stigma. It is crucial for healthcare professionals to establish comprehensive support services aimed at alleviating the stress experienced by these patients and reducing the obstacles they face. Such measures will ultimately enhance treatment compliance and overall well-being.

Antiretroviral Therapy, Compliance, Stress, Psychology, Treatment, Adherence