A study on the prevalence of hearing loss after head and neckradiotherapy with three-dimensionalconformal radiotherapy (۳D-CRT)
محل انتشار: مجله فیزیک پزشکی ایران، دوره: 15، شماره: 0
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 53
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شناسه ملی سند علمی:
JR_IJMP-15-0_074
تاریخ نمایه سازی: 29 آذر 1402
چکیده مقاله:
Introduction:Radiotherapy (RT) plays an important role in treatment of head and neck cancers. In almost ۷۵% of patients with head and neck cancers, RT as the main treatment method is used in order to radical or palliative treatment. Hearing loss is one of the side effects of RT for patients whose inner ear is included in radiation field. The aim of this study was to evaluate the prevalence of hearing loss in patients with head and neck cancers who had undergone three-dimensional conformal radiotherapy (۳D-CRT). Materials and Methods:In this study ۶۸ ears with an average age of ۴۰.۲ years (range ۱۶-۶۰ years) were studied. Pure tone audiometry was performed at frequencies of ۲۵۰, ۵۰۰, ۱۰۰۰, ۲۰۰۰, ۴۰۰۰ and ۸۰۰۰ Hz. Patients with an acceptable result of audiometry initial test were included in this study. They were evaluated three times: before RT, at the end of RT, and three months after RT. The patient s’ treatment planning was performed using Isogray software and statistical analysis of the results was done with SPSS software. Results:The results are based on the CTCAE V. ۴.۰۳ criteria showed ۱۹% ears at the end of radiotherapy, compared with before treatment were suffering from hearing loss. Three months after the end of radiotherapy, the prevalence and severity of hearing loss increased in patients, so that ۳۷% of the ears having hearing loss. Results Statistical analysis showed that at all frequencies studied, the threshold of hearing at the end and three months after the end of radiotherapy compared to baseline, significantly changed (p≤۰.۰۰۱). Conclusion:Considering the high prevalence of hearing loss, ۳۷% just three months after the end of radiotherapy, and progressive with time of this complication (an increase of ۱۸% in ۳ months), post-treatment auditory care is very important for these patients.
کلیدواژه ها:
نویسندگان
Sohaila Yazdani
MSc of Medical Physics, Department of Medial physics, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Karim Khoshgard
Assistant Professor, Department of Medial physics, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mehran Yarahmdi
Assistant Professor, Department of Medical physics, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Negin Farshchian
Assistant Professor, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.