Fatemeh Abbasi - Department of Infectious Diseases, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
Batool Amiri - Clinical Research Development Center, The Persian Gulf Hospital, Bushehr University of Medical Sciences, Bushehr, Iran
Zahrasadat Jalalian - Department of internal medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
Amin Sedaghat - School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran

BACKGROUND AND ABJECTIVEFever and neutropenia will have serious effects on the treatment system and the patient by prolonging the hospitalization process, forcing the dose reduction of chemotherapy drugs, taking multiple antibiotics and finally increasing the costs.MATERIALS AND METHODSThis descriptive-analytical cross-sectional study was conducted on ۲۱ patients with fever and neutropenia hospitalized in the oncology department of the Persian Gulf Martyrs Hospital in Bushehr from April ۱۴۰۰ to September ۱۴۰۱.RESULTS AND DISCUSSIONIn the examination of the cultures sent from the patients, gram-negative bacteria prevailed and simultaneously, several types were resistant to antibiotics. High antibiotic resistance was observed in the family of cephalosporins and fluoroquinolones. On the other hand, aminoglycosides were the most sensitive. According to the investigation, in ۷۶% of our patients, the site of involvement was unknown, and Gram-negative organisms were predominant in the positive samples.CONCLUSIONAccording to the pattern of antibiotic resistance, it is recommended to send suitable samples for culture from all suspicious areas when starting antibiotics, and to pay attention to the microbial pattern in order to reduce costs and indiscriminate use of different antibiotics.

cancer, neutropenia, antibiotics