Seyedeh Habibeh Hosseini - Department of Reclamation of Arid and Mountainous Region, Natural Resources Factually,the University of Tehran, Karaj, Iran
Hossein Azarnivand - Department of Reclamation of Arid and Mountainous Region, Natural Resources Factually,the University of Tehran, Karaj, Iran
Mohammad Reza Naghavi - Agronomy and Plant Breeding Department (APBD), College of Agriculture and Natural Resources, the University of Tehran, Karaj, Iran

Medicinal use of the opium poppy (Papaver somniferum L) has ancient history, but the isolation of morphine was not described until the early nineteenth century. Morphine is the most important alkaloid of opium poppy in the last 50 years. In the morphine pathway has been reported togenerate morphine in this species, CODM has a crucial role as the gene coding the enzymeresponsible for demethylation of codeine to morphine. In this study we extract of CODM genesequence from Papaver fogax and Papaver oriental. The sequence of this gene via in silico technique converted to the protein sequence. After this step we use the bioinformatics tools for analysis of these sequences.

CODM gene, Papaveraceous species, Homology modeling