Marina Mamaladze - Department of Odontology, Tbilisi State Medical University, Dental Clinic, Training and Research Center UNIDENT, Tbilisi, Georgia
Natia Nizharadze - Department of Odontology, Tbilisi State Medical University, Dental Clinic, Training and Research Center UNIDENT, Tbilisi, Georgia
Tamar Shavadze - Department of Odontology, Tbilisi State Medical University, Dental Clinic, Training and Research Center UNIDENT, Tbilisi, Georgia
Ketevan Shalashvili - I.Kutateladze Institute of Pharmacochemistry, Tbilisi State Medical University, Tbilisi, Georgia

Introduction: It is widely known that, plant Cotinus coggygria-Trimli leaves diverse biological activity, including in dental practice. Materials and methods: Our objective was a clinical study of aqueous extract from the leaves of Cotinus coggygria Scop-Trimli cultivated in Georgia by Institute of Pharmacochemistry for industrial scales. Extracts of Trimlia smooth wash, was used in patients for therapy and prophylaxis of oral mucosa and periodontal diseases. Results: Clinical research revealed high antimicrobial activity and anti-inflammatory efficacy of extract. It should be noted that at next day from preparation usage was achieved significantly decrease of swelling, bleeding, pain of periodontal tissues as well as plaque performance reduction on teeth. Conclusion: The study is in progress in odontology, particularly in endodontic practice as tooth root canal irrigation solution, to reveal high antimicrobial potential of aqueous extract Cotinus coggygria against infected root canal microbes, especially against Enterococcus faecalis, Escherichia coli, which are resistant to widely used sodium hypochlorite (NaOCl) antiseptic agent

Cotinus coggygria, Clinical medicine, Dentistry, Antimicrobial activity