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Electospinning of Cyclodextrin Functionalized Chitosan Nanofibers as Drug delivery System

عنوان مقاله: Electospinning of Cyclodextrin Functionalized Chitosan Nanofibers as Drug delivery System
شناسه ملی مقاله: ISPST10_490
منتشر شده در دهمین سمینار بین المللی علوم و تکنولوژی پلیمر در سال 1391
مشخصات نویسندگان مقاله:

Maryam Bazhban - Textile Department,University of Guilan, Rasht, Iran.
mahdi nouri - Textile Department,University of Guilan, Rasht, Iran.
Javad Mokhtari - Textile Department,University of Guilan, Rasht, Iran.

خلاصه مقاله:
Cyclodextrins(CDs) are a family of cyclic oligosaccharides, composed of D-glucose units[1].Grafting CD molecules onto chitosan(CS) reactive sites(CS-g-β-CD) may lead tomolecular carrier that increase the transport properties of CD and mucoadhesive properties of CS[2]. In this study wedescribe the preparation of a novel type of biodegradablenanofibers from a poly (vinyl alcohol)(PVA)/CS-g-β-CD blends via electrospinning.PVA was used as a non-ionogenicpolymer partner due to it being a non-toxic,watersoluble, biocompatible and biodegradable synthetic polymer[3,4,5].The effects of the spinning solutioncomposition on the average fiber diameters and morphology of the PVA/CS-g-β-CD electrospun fibres have been studied.

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/579857/