Fatemeh Hajimanoochehri - Qazvin University of Medical Sciences, Qazvin, Iran
Navid Mohammadi - Tehran University of Medical Sciences, Tehran, Iran
Neda Kasirian - Qazvin University of Medical Sciences, Qazvin, Iran

Background:Small cell carcinoma (SC) is a rare tumor in gastrointestinal tract but esophagus is the mostfrequent site for extra pulmonary SC . It has distinctive histological & clinical features .Theaim of this study was determination of frequency and demographic aspects of SC in comparewith total esophageal cancers.Materials and Methods:In a hospital-based retrospective study through (1989-2008), all pathology reports ofesophageal biopsies which were obtained by endoscopy and had diagnosis of malignancywere extracted. Demographic and histological variables were analyzed by statistical PSWA18.1 BMI soft ware.Results:405 cases of esophageal cancer were obtained .The mean age was 66.3 (±11.8). The youngestand oldest patients were 27 and 100 years old. 245 cases were male and male/ female ratiowas 1.53.Squamous cell carcinoma was the most common type (64.4%) and adenocarcinoma(22%) was the second most. 10.2 % of the cases were poorly differentiated carcinoma withuncertain squamous or adenoid differentiation. Other types of malignancy were 14 cases(3.4%) including 10 cases of SC carcinoma .They were 7 men and 3 women and male/ femaleratio was 2.33. The youngest and oldest patients with SC were 63 and 89 years old and themean age was 72.6.Conclusion:SC carcinoma constituted 2.5% of all esophageal malignancy. It was most common typeamong rare esophageal cancers .The mean age and male/female ratio of SC were higher thanthose which were accounted for all of esophageal cancers. Frequency of SC among totalesophageal cancers was close in similar studies.

Small cell carcinoma, esophageal cancer, demographic aspects