Mina Sadat Naderi - Department of Photo Healing and Regeneration, Medical Laser Research Center (MLRC), Yara Institue, ACECR, Tehran, Iran
Saeed Shams - Department of Photo Healing and Regeneration, Medical Laser Research Center (MLRC), Yara Institue, ACECR, Tehran, Iran
Seyed Mehdi Tabaie - Department of Photo Healing and Regeneration, Medical Laser Research Center (MLRC), Yara Institue, ACECR, Tehran, Iran
Mehdi Reshadi - Department of Photo Healing and Regeneration, Medical Laser Research Center (MLRC), Yara Institue, ACECR, Tehran, Iran

Wound healing is a complex process with many potential factors that can delay healing. There is increasing interest in the effects of bacteria on the processes of wound healing. Wound infection is deleterious to wound healing, but the diagnosis of wound infection is controversial. Thus, the detection of the bacteria on the wound site is so important. There are several methods for the detection of the pathogenic bacteria. Nowadays, using the gold nano particle-based biosensor for the detection of the microorganisms is considered due to owing some properties such as unique optical and electronic properties, shape size-dependent properties, ease of bio-conjugation and non-cytotoxicity. So, this study aims to assess, through a systematic literature review, the application of gold nanorods- based biosensor for the identification of the bacteria on the wound site. For this purpose, we conducted an electronic search in all database for published articles. Most studies demonstrated that the detection of the bacteria using gold biosensors is useful because of practical, rapid, simple, sensitive as well as reliable. The results show that use of the nanotechnology applications in various fields of medicine, especially in the detection of the microorganisms, is growing interest.

Wound, Diagnosis, Biosensor, Gold nanorods