Sayed Amin hoseyni - Chemical Engineering Department, Faculty of Engineering, University of Kashan
Mohsen Ashjari - Chemical Engineering Department, Faculty of Engineering, University of Kashan

Modification of proteins are attractive object for therapeutic agent, biotechnology, nanotechnology. PEGylation can be good selection because of it’s biocompatible, uncharged, and amphipathic polymer. Here modification of WPI with mPEG was investigated. In other to efficiene conjugate of mPEG and WPI, an additional speacer such aminoacid should be used. FTIR analysis was reveals formation of new bonding that proved successful conjugation. The wide range of applications where the obtained conjugates are used, including drug delivery and treapatic agents is a testament to their promising properties and potential to impact even more fields.This was a novel method for modification of PEGylation.

conjugation, PEGylation, Whey protein isolate, aminoacid.