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Ascertainment of Full Sleep and Partial Sleep Deprivation Effects on the Brain Function by Resting State Network Templates

عنوان مقاله: Ascertainment of Full Sleep and Partial Sleep Deprivation Effects on the Brain Function by Resting State Network Templates
شناسه ملی مقاله: HBMCMED06_024
منتشر شده در ششمین کنگره بین المللی نقشه برداری مغز ایران در سال 1398
مشخصات نویسندگان مقاله:

Samar Rekabpour - Institute of Medical Science and Technology, Shahid Beheshti University, Tehran, Iran
Mohammad Taha Pourmohammad - Institute of Medical Science and Technology, Shahid Beheshti University, Tehran, Iran
Negin Riazati - Institute of Medical Science and Technology, Shahid Beheshti University, Tehran, Iran
Mostafa Mahdipour - Institute of Medical Science and Technology, Shahid Beheshti University, Tehran, Iran

خلاصه مقاله:
Partial sleep deprivation (PSD) occurs when a person gets less sleep than is needed to feel awake and vigilant. This may have significant effects on brain functions. The aim of this paper is to study the effects of PSD on brain functions in resting-state.Method Full data is available at https://openfmri.org/dataset/ds000201/ including 6 participants experiencing full and PSD sleep. Data acquisition method and subject selection criteria are explained in the paper [1]. Brain functions had been analyzed utilizing group-ICA (constrained ICA using oxford functional template at https://www.fmrib.ox.ac.uk/datasets/brainmap+rsns/) applied to the patients’ gray matters, in resting-state images. The components had been back-projected to the subject level using dual regression method and the results had been compared with permutation testing.Results Using ICA algorithm, get 20 components with ICA. Comparing each component in group level with related individual level with the TFCE corrected p-value, we found brain areas that showed the functional differences between two sessions. The p-value was chosen 0.1 since at first we set it 0.05 and observed no significant results.Conclusions As observed, comparing two sessions in functional space using their independent components, had no results because we cannot find any statistically significant differences. However, reducing the minimum value to 0.1 gives us some dissimilarity between images shown below. Therefore we can conclude that our test has a null result. Perhaps this result is the consequence of the low number of subjects. Hence, with a similar test, our results are the same with the results that are obtained by two papers ([1],[2]). As this papers have concluded, one possible interpretation is that PSD and the associated moderate sleepiness may not cause changes in brain functions.

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/951688/