Alireza Nikseresht - Shiraz University of Medical Sciences, Shiraz, Iran

In this review we want to overview all typical optic neuropathy and their characteristic and specially we want to discuss important clinical and imaging red flag for optic neuritis for neurologist to differentiat them from atypical optic neuritis.Because different causes of optic neuropathy have different treatment and diagnostic approach. For example, sever vison loss can be due NMOSD and its treatment can beresponsive to plasmaexchang than corticosteroid alone. we must review red flag for typical optic neuritis before considering of treatment and diagnosis