Oxidative Stress Responses in Goldfish (Carassius auratus) Induced by Zinc Sulfate (ZnSO4)

The current research aimed to examine the effect of zinc sulfate (ZnSO4) on antioxidant capacity in goldfish (Carassius auratus). Juvenile goldfish (3.3 g) were fed purified diets based on casein as a protein source and containing different levels of supplementary zinc sulfate (0, 25, 75 and 150 mg ZnSO4/kg diet) for 60 days. The results showed that fish fed a diet supplemented with 150 mg kg-1 Zn had a significance (P<0.05) greater antioxidant amount than those fed diets of 0, 25 and 75 mg kg-1zinc sulfate. ZnSO4 increased significantly superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) activities. In brief, our findings indicate that ZnSO4 could increase fish antioxidant activity and stimulates physiological parameters in goldfish.