Impact Of High NaCl Concentration In Drinking Water On Health Of Different Human Organs; Review Article

Sodium chloride (NaCl) that commonly named dietary salt is most important electrolyte in our body. NaCl has many role in health of many human organs. Normal function of CNS, cardiovascular system, kidney and other organs are dependent to NaCl concentration. NaCl concentration is controlled very conscious in blood. Any small changes in NaCl concentration in blood can cause major changes in blood volume and may lead many pathophysiology conditions like: heart disease, stroke, kidney failure, encephalopathy, high blood pressure. Due to geographical diversity, in different region, people are exposed with different range of NaCl concentration. This is a novel issue that how much of the health of people from different region is related to salt level. Because of the importance of this issue, the aim of this study is to review studies that performed about in this issue,  advantages and disadvantages of different level of NaCl in health of people from different region and in each of region which disease more common due to  impaired NaCl homeostasis.