Cardiac arrhythmia due to ledipasvir/sofosbuvir Iranian counterpart, commercially named as Ledibiox: A case report

سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 288

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شناسه ملی سند علمی:

JR_JCTM-8-3_008

تاریخ نمایه سازی: 19 دی 1399

چکیده مقاله:

Sofosbuvir is an antiviral drug that entirely revolutionized the treatment of hepatitis C. This drug has an Iranian commercial brand, which is known as Ledibiox. Several adverse events have been reported with this drug, including syncope, pancolitis, and exacerbated pulmonary arterial hypertension; however, arrhythmia rarely has been described through the literature. Here, we report a 40-year-old Caucasian man who presented with chest pain, tachycardia, blurred vision, and severe headache; whose electrocardiography showed an atrial tachycardia along with a block. It seems that Sofosbuvir toxicity can cause arrhythmia, and the drug prescription should be halted in this situation.

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نویسندگان

Alireza Heidari Bakavoli

Cardiologist, Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Alireza Ghodsi

Medical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Alireza Omranzadeh

Medical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Moniba Bijari

Medical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Sara Hosseini

Cardiologist, Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

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