Comparison of Helicobacter Pylori Seroprevalance between Acne Rosacea and Healthy Group

Background and Objective: Acne rosacea is a chronic skin disease with unknown etiology. Some reports have suggested an increased prevalence of helicobacter (H) pylori infection in patients with acne rosacea but it is controversial. This study was designed to compare the prevalence of H pylori between the acne rosacea patients and the healthy control group. Materials and Methods: This case-control study was performed on ۳۰ patients with acne rosacea and ۶۰ healthy individuals as a control group. ۵ mL blood was taken from each person and anti-H pylori IgG was measured by enzyme-linked immunosorbent assay. Results: Mean age was ۴۵.۸±۱۴.۰۵ years in acne rosacea patients and ۴۱.۴±۱۲.۳ years in control group. Seventeen (۵۶.۷%) of patients and fifty two (۸۶.۲%) of controls were infected by H pylori (P=۰.۰۰۲), but mean serum anti-H pylori IgG level was significantly higher in acne rosacea patients comparing to healthy control group (۱۳۹.۴۹±۱۷۴.۱۵ g/mL vs ۳۸.۸۷±۲۳.۵۰, P=۰.۰۰۵). Conclusion: Despite increased mean serum anti-H pylori IgG levels in acne rosacea patients, H pylori was more prevalent in healthy control group, in this study.