Acute liver failure due to Cassia floribunda: case report of three children from a family.
محل انتشار: دوفصلنامه طب گیاهی پیشرفته، دوره: 4، شماره: 3
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 234
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شناسه ملی سند علمی:
JR_JHPH-4-3_004
تاریخ نمایه سازی: 11 خرداد 1400
چکیده مقاله:
Liver is the largest and most vital organ in human body and able to detoxify several chemical compounds. Acute liver failure (ALF) is a rare devastating process that can leads to urgent liver transplantation. In this study we introduce ۳ children of a family with an accidental intoxication of Cassia Floribunda which causes ALF. The first case is a four-year-old girl with an icter's complaints and drowsiness after eaten plant in the garden while playing with her sister and friend ۳ days ago. At the beginning her GCS was ۱۰, vital signs were normal, sclera was icteric and pupil has normal size and was reactive to the light. Initial tests showed leukopenia, anemia, thrombocytopenia, increase of liver enzymes , coagulopathy , hypoglycemia. With diagnosis, fulminant liver deficiency and hepatic encephalopathy, the patient transferred to PICU and GCS reduced. her general appearance became better ,consciousness increased, lab test findings improvedand and discharged after ۱۱ days.Second and third cases presented to emergency with similar complaints without icteric, vital signs and other examinations were normal . Initial tests reported reduced platelets, increase liver enzymes , Without hypoglycemia. treatment was started for patient by intravenous ranitidine and monitored in emergency . Two days after discharged. But in third case platelets increased.ALF in children is a serious problem that can lead to death or need to liver transplantation. When evaluate the causes of ALF, poisoning due to plants should be kept in.
کلیدواژه ها:
نویسندگان
Maryam Montazeri
Gorgan University od medical sciences
Mohammad Sobhani Shahmirzadi
Assistant professor of Pediatric Gastroenterology, Neonatal and Children’s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran
Samane sharifi najjari
Resident of pediatric, Golestan University of Medical Sciences, Gorgan, Iran
Mohammadreza Ebadpour
Students Research Committee, Golestan University of Medical Sciences, Gorgan, Iran