Effect of combination of honey, saffron (Crocus sativus L.) and sedge (Cyperus rotundus L.) on cognitive dysfunction in patients with Alzheimer's disease
محل انتشار: دوفصلنامه طب گیاهی پیشرفته، دوره: 1، شماره: 2
سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 230
فایل این مقاله در 6 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JHPH-1-2_003
تاریخ نمایه سازی: 12 خرداد 1400
چکیده مقاله:
Background and aims: Alzheimer's disease is a progressive disorder of nervous system that leads to dementia in patients. This study was conducted to determine the effect of combination of honey, saffron (Crocus sativus L.) and sedge (Cyperus rotundus L.) on cognitive dysfunction in patients with Alzheimer’s disease. Methods: This double-blinded clinical trial study enrolling a sample size of ۳۰ subjects was conducted per cross-over method. The patients with mild Alzheimer's disease obtaining the scores ۱۲ ≥ in cog-ADAS scale were enrolled into the study. The participants were randomly assigned into two groups of A and B. During the first ۲ months in group A, placebo was given, and group B underwent treatment with the combination under study. After a one-month period of washout, the same procedure was run reversely in two groups. Finally, the data analysis was done by SPSS software using descriptive and analytical tests. Result: Mann-Whitney test indicated no difference in mean cognitive dysfunction between two groups in neither of periods (P>۰.۰۵). Also, Friedman test showed no change in cognitive dysfunction during the study in neither of groups (group A: P=۰.۲۸۷, group B: P=۰.۱۵۸). Conclusion: Simultaneous use of honey, C. rotundus and C. sativus has no more pronounced effect than placebo on cognitive dysfunction in patients with mild to moderate Alzheimer's disease. It is recommended that future studies of this compound be done on patients of younger age and its preventive effects be addressed.
کلیدواژه ها:
نویسندگان
Nahid Jivad
Neurology Dept., Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
Nadereh Zare-Hassanabadi
General practitioner, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Mahmoud Azizi
Mycology Dept., Shahid Sadoughi University of Medical Sciences, Yazd, I.R. Iran
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :