Electrochemotherapy for Treatment of Cutaneous Breast Cancer Metastases: A Review

Background: Electrochemotherapy is a relatively new technique in thetreatment of skin metastases that are not amenable to conventional therapy. Its usein breast cancer is now established in many European centers.Methods: Published literature of electrochemotherapy in terms of its scientificbasis, current clinical practice of breast cancer treatment providers, as well as thefuture directions for the technology has been reviewed.Results: Collective global experience of the last ۱۰ years has demonstratedElectrochemotherapy is a safe, well-tolerated and effective treatment of cutaneousbreast cancer metastases and good outcome characteristics have been identified.However, successful treatment requires appropriate patient selection.Conclusions: Electrochemotherapy is now established as a standard of care forcutaneous metastases. Its future use may extend to gene therapy and the treatmentof visceral tumors.