Identification of Key Proteins in different stages of Hepatocellular carcinoma (HCC) compared to Normal Liver tissue with a Systems Biology approach

سال انتشار: 1400
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 320

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شناسه ملی سند علمی:

ICSB04_024

تاریخ نمایه سازی: 20 مهر 1400

چکیده مقاله:

Liver cancer is the sixth most common cancer worldwide, among different liver malignancies, hepatocellular carcinoma (HCC) is the most prevalent. Bad prognosis and increasing incidence rate of liver cancer leads to extensive studies on it.in this study with a holistic look to associated proteins in liver cancer in a network and utilizing bioinformatics tools to analyze them, key proteins of this disease that can be use as therapeutic or diagnostic targets, have been identified with a systems biology approach

نویسندگان

Farzaneh shalileh

National institute of Genetic Engineering and Biotechnology,Tehran,Iran;Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Scien

shahram parvin

Chemical injuries Research Center,Systems Biology and Poisonings Institutes,Baqiatallah university of Medical Scciences,Tehran,Iran;

binazir khanabadi

Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Saeedeh sadat Beheshti Shirazi

Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Fatemeh Naderi Noukabadi

Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Ali Seyed Salehi

Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.