Molecular and genetic aspects of odontogenic tumors: a review

سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 101

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شناسه ملی سند علمی:

JR_IJBMS-18-6_001

تاریخ نمایه سازی: 3 آبان 1400

چکیده مقاله:

Odontogenic tumors contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. Odontogenic tumors are usually extraordinary with assessed frequency of short of ۰.۵ cases/۱۰۰,۰۰۰ population for every year. The lesions such as odontogenic tumors are inferred from the components of the tooth-structuring contraption. They are discovered solely inside the maxillary and mandibular bones. This audit speaks to experiences and cooperation of the molecular and genetic variations connected to the development and movement of odontogenic tumors which incorporate oncogenes, tumor-silencer genes, APC gene, retinoblastoma genes, DNA repair genes, onco-viruses, development components, telomerase, cell cycle controllers, apoptosis-related elements, and regulators/controllers of tooth development. The reasonable and better understanding of the molecular components may prompt new ideas for their detection and administrating a better prognosis of odontogenic tumors.

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نویسندگان

Kavita Garg

Department of Oral Pathology, Chandra Dental College, Barabanki, India

Shaleen Chandra

Department of Oral Pathology, King George Medical College, Lucknow, India

Vineet Raj

Department of Oral Pathology, Saraswati Dental College and Hospital, Lucknow, India

Wamiq Fareed

Department of Oral Surgery, Taibah University College of Dentistry, Al Madinah Al Munawwarah Saudi Arabia

Muhammad Zafar

Department of Restorative Dentistry, Taibah University College of Dentistry, Al Madinah Al Munawwarah, Saudi Arabia

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