Medical Evaluation of Test Results Related to Covid ۱۹ in Iranian Hospitals Using QUADAS-۲ to Evaluate the Quality of Studies and Meta-Analysis Using Stata / MP v.۱۶ Software

The aim of current study was to evaluate the outcome of some laboratory tests and accuracy of diagnostic tests for patients with COVID-۱۹. The QUADAS-۲ tool was utilized to quality assessment of diagnostic accuracy studies. For data extraction, two reviewers blind and independently extracted data from abstract and full text of studies that included. ۹۵% confidence interval for effect size with fixed effect model and Inver-variance method were calculated. Meta-analysis was performed using Stata/MP v.۱۶ software. ۴۶۹ studies were reviewed, of which the full text of ۵۲ studies was reviewed and finally twenty-two studies were selected for meta-analysis.  Mean differences of Alanine transaminase was ۳.۴۰ U/L (MD, ۹۵% CI -۲.۴۵, ۹.۲۵), correlation between Alanine transaminase and severe COVID-۱۹ was not significantly. Stool, feces, rectal swabs ۲۵% (ES, ۹۵% CI ۰.۳۲, ۰.۸۲), Urine ۱% (ES, ۹۵% CI ۰.۰۵, ۰.۵۸), overall sensitivity of PCR for detection of COVID-۱۹ was ۴۴% (ES, ۹۵% CI ۰.۱۹, ۰.۶۸), less sensitive observerd when PCR detection of COVID-۱۹.  Evidence revealed that at the time of admission of patients with COVID-۱۹, a specific laboratory model can be used to perform relevant tests and make decisions about patients. PCR using sputum samples was highly sensitive for detecting COVID-۱۹ and after that computed tomography of the chest was identified with high sensitivity.