Characterization of Disturbed Hemodynamics due to Stenosed Aortic Jets with a Lagrangian Coherent Structures Technique
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 149
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شناسه ملی سند علمی:
JR_JAFM-11-2_008
تاریخ نمایه سازی: 18 دی 1400
چکیده مقاله:
The aortic valve is located at left ventricular outlet and is exposed to the highest pressure in the cardiovascular system. Problems associated with the valve leaflet movement can cause complications for the heart. Specifically, aortic stenosis (AS) arises when aortic leaflets do not efficiently open. In the present study, Lagrangian Coherent Structures (LCSs) were utilized by processing a variety of Computational Fluid Dynamics (CFD) models velocity vector data further to identify the characteristics of AS jets. Particularly, effective orifice areas (EOA) for different cases were accurately identified from unstable manifolds of finite time Lyapunov exponent (FTLE) fields. Calcified leaflets were modeled by setting the leaflet's Young modulus to ۱۰ MPa and ۲۰ MPa for moderately and severely calcified leaflets respectively while a healthy leaflet's Young modulus was assigned to be ۲ MPa. Increase in calcification degree of the leaflet caused destruction of the vortex structures near the fibrosa layer of the leaflet indicating a malfunctioning for the movement mechanism of the leaflet. Furthermore, when we analyzed stable manifolds, we identified a blockage region at the flow upstream due to the stagnant blood here. Compared to a healthy case, for the calcified valve, this blockage region was enlarged, implying an increase in AS jet velocity and wall shear stress on leaflets. As a conclusion, results from the present study indicate that aortic leaflet malfunctioning could be accurately evaluated when LCS technique was employed by post processing velocity vector data from CFD. Such precise analysis is not possible using the Eulerian CFD approach or a Doppler echocardiography since these methods are based on only analyzing instantaneous flow quantities and they overlook fluid flow characteristics of highly unsteady flows.
کلیدواژه ها:
نویسندگان
A. B. Olcay
Yeditepe University, Mechanical Engineering Department, Atasehir, Istanbul, ۳۴۷۵۵, Turkey
A. Amindari
Istanbul Technical University, Mechanical Engineering Department, Istanbul, Turkey
K. Kirkkopru
Istanbul Technical University, Mechanical Engineering Department, Istanbul, Turkey
H. Yalcin
Qatar University, Biomedical Research Center, PO Box ۲۷۱۳, Doha, Qatar