Research Article: Histological study and evaluation of Hsp۷۰ gene expression in gill and liver tissues of goldfish (Carassius auratus) exposed to Zinc oxide nanoparticles

سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 110

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شناسه ملی سند علمی:

JR_JIFRO-20-3_011

تاریخ نمایه سازی: 23 بهمن 1400

چکیده مقاله:

In parallel with the increased use of nano-sized metallic materials, the possibility of their release into the environment has increased in recent decades. However, there is not sufficient information on the toxic potential of these materials on different aspects of the life history of aquatic organisms. In this study, we investigated the impact of zinc oxide nanoparticles (ZnO-NPs) on goldfish by studying histopathological alteration and Hsp۷۰ gene expression in gill and liver tissues. The results showed that after exposure to different concentrations of ZnO-NPs, severe lesions were observed in the gill and liver tissues of goldfish. Expression of Hsp۷۰ significantly increased in comparison with the control group and this increase was observed especially in the initial sampling times. Also expression pattern of Hsp۷۰ is relatively similar in gill and liver tissues of goldfish. Based on the results of the present study, ZnO-NPs, as widely used nanoparticles can endanger the health of goldfish and further studies are needed to evaluate its potential toxic effects.

نویسندگان

M. Harsij

Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran

H. Paknejad

Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran

M. Khalili

Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

H. Jafarian

Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran

S. Nazari

Cold-water Fishes Genetic and Breeding Research Center, Iranian Fisheries Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Yasouj, Iran

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  • Farmen, E., Mikkelsen, H., Evensen, Ø., Einset, J., Heier, L., ...
  • Federici, G., Shaw, B. J. and Handy, R.D., ۲۰۰۷. Toxicity ...
  • Garrido, C., Gurbuxani, S., Ravagnan, L. and Kroemer, G., ۲۰۰۱. ...
  • Golshan, M., Hatef, A., Habibi, H. and Alavi, S., ۲۰۲۰. ...
  • DOI: ۱۰.۲۲۰۹۲/IJFS.۲۰۲۰.۱۲۲۷۹۸ ...
  • Gottschalk, F., Sun, T. and Nowack, B., ۲۰۱۳. Environmental concentrations ...
  • Hao, L., Chen, L., Hao, J. and Zhong, N., ۲۰۱۳. ...
  • Hu, Y.L., Qi, W., Han, F., Shao, J.Z. and Gao, ...
  • Johnston, B.D., Scown, T.M., Moger, J., Cumberland, S.A., Baalousha, M., ...
  • Katuli, K.K., Massarsky, A., Hadadi, A. and Pourmehran, Z., ۲۰۱۴. ...
  • Livak, K.J., Schmittgen, T.D., ۲۰۰۱. Analysis of relative gene expression ...
  • Miandare, H.K., Niknejad, M., Shabani, A. and Safari, R., ۲۰۱۶. ...
  • Mills, L.J. and Chichester, C., ۲۰۰۵. Review of evidence: are ...
  • Mishra, A.K. and Mohanty, B., ۲۰۰۸. Acute toxicity impacts of ...
  • Palermo, F.A., Cocci, P., Nabissi, M., Polzonetti-Magni, A. and Mosconi, ...
  • Roy, S. and Bhattacharya, S., ۲۰۰۶. Arsenic-induced histopathology and synthesis ...
  • Ryan, J.A. and Hightower, L.E., ۱۹۹۴. Evaluation of heavy‐metal ion ...
  • Schett, G., Steiner, C.W., Gröger, M., Winkler, S., Graninger, W., ...
  • Singh, N., Manshian, B., Jenkins, G.J., Griffiths, S.M., Williams, P.M., ...
  • Trevisan, R., Flesch, S., Mattos, J.J., Milani, M.R., Bainy, A.C.D. ...
  • Xiong, W., Sun Y. and Zou., M., ۲۰۱۳. Molecular cloning, ...
  • Yang, X., Gondikas, A.P. Marinakos, S.M., Auffan, M., Liu, J., ...
  • Yoo, J. and Janz., D., ۲۰۰۳. Tissue-specific HSP۷۰ levels and ...
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