Influence of albocarbon-cyclic hybridization on biomedical activities: A review

There is an excellent demand in biomedical sciences for novel drug-like compounds with the best therapeutic benefits and minor adverse effects. The albocarbon moiety is seen to be abundantly available in nature, prompting various investigations to isolate albocarbons and investigate their pharmacological activities. Synthetic albocarbons show various biological properties, including antioxidant, antibacterial, antiproliferative, anti-inflammatory, antifungal, and antiviral effects. The consequences of hybridizing cyclic molecules with albocarbons on their bioactivities have been studied widely in the literature. The bulk of these studies revealed that this hybridization might improve the pharmacological properties of the mother albocarbons. This comprehensive review, which described the most critical and recent examples of such studies, emphasized the structural features of the produced hybrids as potentially bioactive frameworks.