Complications of Tuberculosis Packs and Iron Chelators in Patients with Thalassemia Major in Mostafa Khomeini Hospital in ۲۰۱۸-۱۹
محل انتشار: مجله علوم دارویی و شیمی، دوره: 5، شماره: 4
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 119
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شناسه ملی سند علمی:
JR_JMCH-5-4_017
تاریخ نمایه سازی: 15 فروردین 1401
چکیده مقاله:
Background and Purpose: Thalassemia major (TM) is an inherited hemolytic disease with a high prevalence. Nowadays, no complications have been studied in these patients. Therefore, this study aimed to investigate the complications of tuberculosis packs and iron chelators in patients with TM in Mostafa Khomeini Hospital in ۲۰۱۸-۲۰۱۹.Methods: This cross-sectional study was performed in Mostafa Khomeini Hospital in ۲۰۱۸-۲۰۱۹. All eligible patients' records and necessary information, including age, sex, and periodic tests (cardiac, liver, bone, and hormonal and infectious examinations), were reviewed and collected using a checklist. Data were analyzed using SPSS۲۲ software with a significance level of ۰.۰۵.Results: Enrolled patients were ۹۳ cases with TM. The incidence of osteopenia and osteoporosis (۶۹.۹%) was the most common, and the lowest cases were hypogonadism (۳۵.۵%), hypothyroidism (۹.۷%), heart failure (۵.۴%), hepatitis C (۲.۲%), and liver failure. Hepatitis B and HIV were not seen in these patients.Conclusion: Results demonstrated that the highest rate of complications was related to the bony part of the body structure, which is due to the pathophysiology of the disease. The low rates of heart failure and liver failure were because the patients with this level of complications may not survive for long.
کلیدواژه ها:
نویسندگان
Hassan Nourmohammadi
Department of Internal Medicine, School of Medicine Shahid Mostafa Khomaeini Hospital Ilam University of Medical sciences, Ilam University of Medical Sciences, Ilam, Iran
Hosein Daresh
Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
Elham Shafiei
Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
Mahtab Bonyadi
Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
Ali Hhorshidi
Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
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