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مقالات فارسیISIکنفرانسهاژورنالها

The Effect of Nigella Sativa on Cardio-Metabolic Parameters: A Protocol for A Systematic Review and Meta-Analysis

محل انتشار: فصلنامه تغذیه و امنیت غذایی، دوره: 7، شماره: 2
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 224

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لینک ثابت به این مقاله:
https://civilica.com/doc/1441274

شناسه ملی سند علمی:

JR_JNFS-7-2_013

تاریخ نمایه سازی: 18 اردیبهشت 1401

چکیده مقاله:

Background: Among non-communicable diseases, cardiovascular diseases (CVDs) account for ۴۴% of all deaths. Among natural alternatives, Nigella sativa (NS) exert beneficial effects on cardio-metabolic factors. This is the first systematic review and meta-analysis protocol aimed to identify all the findings relevant to the effects of NS on cardio-metabolic factors among adults. Methods: This study was prepared according to PRISMA-P checklist based on Cochrane Handbook for Systematic Reviews of Interventions. An initial literature search was conducted in various databases using MeSH terms and related synonyms. Trials examining the effects of NS versus control group were included. Main outcomes consisted of blood pressure, lipid and glycemic factors, and atherogenic indices. Seven reviewers independently evaluated titles and abstracts, reviewed full texts, extracted information, and assessed the risk of bias. Methodological quality of each randomized controlled trial was assessed using the Cochrane Handbook and the GRADE system, while Newcastle-Ottawa Quality Assessment Scale was used for non-randomized studies. Continuous data of homogeneous studies were meta-analyzed via STATA. Mean differences were calculated as the effect size with ۹۵% CIs. Heterogeneity assessment, sensitivity analysis, and publication bias were performed. Conclusion: The quality of both randomized and non-randomized studies was assessed. The evidence from this study can provide information for future clinical trials

کلیدواژه ها:

Nigella sativa ، Cardio-Metabolic Factors ، Systematic Review ، Meta-Analysis ، Insulin ، Lipids ، Glycemic Indices ، Blood Pressure

نویسندگان

Elham Razmpoosh

Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Farhang Mirzavandi

Nutrition and Food Security Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Narges Sadeghi

Department of Nutrition, School of Allied Medical Science, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Sara Safi

Nutrition and Food Security Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Nooshin Abdollahi

Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Azadeh Nadjarzadeh

Nutrition and Food Security Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Amin Salehi-Abargouei

Nutrition and Food Security Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. ۳Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

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