Electrochemical Determination of Chloramphenicol in Milk and Eye-drop Using Easily Activated Screen Printed Carbon Electrodes

سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 92

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شناسه ملی سند علمی:

JR_IJAC-8-1_012

تاریخ نمایه سازی: 26 تیر 1401

چکیده مقاله:

An analytical method that offers fast response with a cheap instrument and simple sample preparation is an ideal technique that is required in scientific analysis. Electrochemical sensing is an analytical method that suits the above criteria to determine various samples using different electrode material. Detection of chloramphenicol in agricultural products and drug samples using cheap electrode materials is highly required due to its wide application in agriculture. In this study a cost-effective activated SPCE was made electrochemically to determine chloramphenicol in eye-drop and pasteurized milk. The activation of the SPCE was straightforward and done by cycling ۰.۵ M KOH using LSV techniques. Surface imaging, spectroscopy, and electrochemical analyses showed that there is an effective formation of new functional groups during the activation. The activated SPCE gave a higher peak current for Chloramphenicol during the CV and SWV study using PBS pH ۶.۵ compared to that of the bare one. Utilizing the optimal SWV conditions, a linear calibration curve was obtained in the range of ۰.۰۵‒۱۰۰ µM with quite a small detection limit of ۲۰ nM. In addition to the high sensitivity, stability, and remarkable recovery, the excellent reproducibility makes the activated SPCE applicable in real sample analysis.

کلیدواژه ها:

Chloramphenicol ، Screen Printed Carbon Electrode ، Electrochemical ، Stable ، Activated

نویسندگان

Tesfu Hailu

Department of industrial chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O.Box ۱۶۴۱۷, Ethiopia.

Yaw-Kuen Li

Department of applied chemistry, ۱۰۰۱ University Road, Hsinchu, Taiwan ۳۰۰, ROC

Merid Tessema

Department of chemistry, Addis Ababa University College of Natural and Computational Science, Addis Ababa P.O.Box ۱۱۷۶, Ethiopia.

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