The effect of aerobic exercise on glucose-dependent insulinotropic polypeptide (GIP), body composition and lipids profile in type ۲ diabetes woman patients

Physical activity can be effective in releasing intestinal peptides and insulin secretion, which is important to preventing the progression of type ۲ diabetes. The aim of this study is to investigate the effects of ۸ weeks aerobic training on GIP, body composition and lipid profile of type ۲ diabetic women.Sixteen women with type ۲ diabetes with mean age of ۵۰.۸۱ ± ۴.۹۶, weight of ۷۶.۱۸ ± ۵.۱۵ and body mass index of ۲۹.۳۰ ± ۴.۵۱, were randomly separated into two groups of nine aerobic exercise and seven control subjects. An eight-week program of aerobic exercise is conducted by increasingly running on a treadmill three times a week for ۳۰-۴۵ minutes at ۵۵-۷۵% target heart rate; and fasting blood samples were taken before and ۷۲ hours after the last training session of the subjects.The mean and standard deviation of each variable are derived from descriptive statistics and Shapiro-Wilkes test is used to determine the natural distribution of data. Covariance analysis further used to examine the changes between groups. Aerobic exercise resulted in decreased BMI (p=۰/۰۱), body fat (p=۰/۰۵) and weight (p=۰/۰۱) yet it had no significant effect on GIP, total cholesterol (p=۰/۲۵), HDL (P=۰/۷۴), LDL (p=۰/۷۷).The findings of this study demonstrated that aerobic exercise has no significant effect on GIP and lipid profile, but can have significant effect on body composition parameters in type ۲ diabetic women. We anticipated, continuation aerobic exercise for a longer period of time may also reduce GIP and lipid profile.