Epidemiology and Risk Factors of Diabetic Nephropathy in Children and Adolescents
محل انتشار: مجله بین المللی کودکان، دوره: 10، شماره: 8
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 105
فایل این مقاله در 11 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_INJPM-10-8_002
تاریخ نمایه سازی: 13 شهریور 1401
چکیده مقاله:
Background: Diabetes mellitus is the most common childhood metabolic disease whose prevalence has been increasing worldwide in recent decades. Diabetic nephropathy is one of the most important chronic complications of both types of diabetes (type one and two), which seriously increases the morbidity and mortality of diabetes. The present study evaluated the epidemiology and risk factors of diabetic nephropathy in children with diabetes in the northwestern region of Iran. Method: In this cross-sectional study, ۸۰ diabetic children, ۳۳ (۴۱.۳%) males and ۴۷ (۵۸.۷%) females with a mean age of ۱۶.۶۹± ۴.۵۰ years at the time of assessment, have been identified, evaluated, and followed up in the endocrinology clinic of Tabriz Children's Hospital from ۲۰۰۰ to ۲۰۱۵. The patients were divided into two groups based on the presence or absence of micro- or overt albuminuria, and different variables were compared between the two groups to determine risk factors. Results: The mean age at the diagnosis was ۷.۷۵ ± ۳.۶۹ and the mean duration of diabetes was ۸.۹۸± ۴.۰۷ years. Good glycemic control was presented in ۱۹ (۲۳.۸%), microalbuminuria in ۳۶ (۴۵%), overt albuminuria in ۱ (۱.۳%), and retinopathy in ۵ (۶.۳%) of patients; ۷ (۸.۸%) had hypertension. Chronic kidney disease was found to be stage I in ۹۰% and stage II in ۱۰% of the patients. There was a significant difference between cases with and without albuminuria in terms of age at the time of the study (p=۰.۰۰۳), duration of diabetes (p=۰.۰۲), and serum cholesterol level (p=۰.۰۴). Linear Regression test showed that «the age at diagnosis» has a significant ability to predict the incidence of albuminuria (p = ۰.۰۳). Conclusion: Due to the significant frequency of poor glycemic control in children and adolescents and the high prevalence of albuminuria in them, it is recommended to evaluate the renal function in diabetic children, especially in older patients, those with longer duration of diabetes or poor glycemic control.
کلیدواژه ها:
نویسندگان
Afshin Ghalehgolab Behbahan
Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Arezou Hasanzadeh
Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Siamak Shiva
Pediatric Health Research Center, Department of Pediatrics, Tabriz University of Medical Sciences, Tabriz, Iran.
Zahra Golchinfar
Clinical Research Development Unit of Children Educational and Treatment Center, Tabriz University of Medical Sciences, Tabriz, Iran
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :