Formation, Characterization and Antioxidant Study of Mixed Ligand Complexes Derived from Succinyl Chloride

In the present study, mixed ligand compounds of Mn(II), Ni(II), Co(II), Cu(II), Cd(II) and Hg(II) were synthesized using new Ligand N۱,N۴-bis (pyrimidin-۲-ylcarbamothioyl) succinimide (NPS) derived from [Butanedioyl diisothiocyanate with ۲- aminipyridine] as first ligand, and proline (pro) as second ligand and evaluation of their antioxidant activities for ligand, nickel and cobalt complex towards ۱.۱-Di-phenyl-۲picrylhydrazyl (DPPH) were compared with the standard anti-oxidants (i.e. the ascorbic acid). The materials led to the results that came from exhibiting different activities of the radical scavenging for all of the compounds. The compounds observed were then confirmed through the Fourier-transform infrared (FT-IR), proton nuclear magnetic resonance (۱ HNMR), ultraviolet-visible (UV-vis), micro-elemental analyses (CHNS), thermal analysis (TGA), carbon۱۳ nuclear magnetic resonance (۱۳CNMR), atomic absorption flame (AAF), magnetic susceptibility and conductivity. The proposed geometry for all complexes [M۲(NPS)(pro)۲]Cl۲ was tetrahedral. Furthermore, the antibacterial and antifungal activity was screened for the DMSO solution concerning the ligand (NPS) and its complexes against two kinds of gram; (Staphylococcus aureas) positive and (Esherichia coli) negative and against (Candida albican) fungi.