Synthesis, Characterization, and Antimicrobial Activity By Coordinated Metals Ions Rh+۳, Au+۳ with Sodium Fusidate and ۲,۲/ Bipyridine as Ligands

To reflect modern practice in lab experiments, they should include a range of elements. Mixed new complexes of metal chloride for Rh(III) and Au(III) synthesis by the condensation reaction of metals with sodium fusidate as a primary ligand with the secondary ligand represented by ۲,۲-bipyridine (L/) in boiling ethanol and synthetic tasks are accompanied by characterization and analysis in the solid state based on the results of the color, melting points, metal composition percent and other elements (C, H, and N), the spectroscopic measurement acts by UV-Vis and FT-IR, magnetic susceptibility, and electrical conductivity measurements. The results of this study reveal the coordination sites for the ligands with the metal ions as bidentate through two oxygen atoms of the sodium fusidate, while bipyridine via diimine nitrogen atoms. Analytical and spectroscopy studies disclosed octahedral structure for Rh(III) complex and square planner structure of Au(III) complex. The ligands and both inclusions of new complexes were screened against bacterial and fungal strains (Escherichia coli as gram (-), Staphylococcus aurous as gram (+) and Candida albicaons) at three selected concentrations (۵۰, ۱۰۰, and ۲۰۰ ppm) and their preliminary results compounds exert the cell surface damage observed by scanning electron microscopy (SEM) and the Au(III) complexes exhibit the superior antimicrobial activity particular in a high concentration (۲۰۰ ppm).