Determination of the prevalence of clinical signs of Aspirin and NSAID poisoning in patients referring to Ahvaz Razi Hospital
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 93
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شناسه ملی سند علمی:
JR_PJMT-11-3_002
تاریخ نمایه سازی: 7 آبان 1401
چکیده مقاله:
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of drugs that are among the most commonly prescribed drugs worldwide. Due to the ease of access and widespread use of these drugs, many cases of intentional and accidental poisoning of these compounds have been reported.The aim of this study was to determine the prevalence of the clinical signs of drug toxicity with aspirin and NSAIDs in patients referred to Razi Hospital in Ahwaz.Methods: In this study, patients suffering from aspirin and NSAIDs poisoning referred to Razi Hospital during ۲۰۱۳-۲۰۱۵ were included in the study. Information reviewed from their stored records includes clinical presentation, demographic information, reference data, and treatment options.Results: In this study, ۷۹.۵% were female respondents and ۲۰.۵% were male, and Faye and Kramer coefficients confirmed the existence of a strongly separate relationship between the gender variable and the first clinical signs of poisoning. The results showed that Diclofenac with ۲۷% had the highest toxicity and nausea was the most common symptom in all drug toxicity with aspirin and NSAIDs. Nausea is a common symptom of poisoning with these drugs. There was a significant relationship between laboratory changes with the type of drug and the need for ICU admission, and this relationship was not strong due to the index values.Conclusion: According to the results, most of the patients were aged between ۱۴-۲۴ years old. Nausea was the most common symptom in all drug toxicity with aspirin and NSAIDs.
کلیدواژه ها:
نویسندگان
Maryam Shirani
Department of Pharmacology and Toxicology, Pharmacy School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Ali Hassan Rahmani
Department of Pharmacology and Toxicology, Pharmacy School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Parechehr Heidarian
School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
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