Breast Cancer Prevalence and Management in Hispanic Women: Comparison to Black and White Women at a Regional Medical Center

Background: While stage and grade of breast cancer determines prognosis andoutcome, race also impacts survival. While Black and White women have beenstudied, data for Hispanic women is sparse.Methods: Age-matched Hispanic, Black and White women diagnosed/treatedwith breast cancer at a single institution were retrospectively evaluated regardingprevalence, treatments and outcomes.Results: Overall, ۱۲۰ women were included in the study (۴۰ per race). Nodemographic/histologic variables were significantly different among races.ER+/PR+ tumors were less frequent in Hispanics than Whites, but higher thanBlacks. Prevalence of triple negative breast cancers in Hispanic women wasbetween the Black and White cohorts (p=۰.۰۲۵ and p=۰.۰۱۱, respectively). Stage IIand III diagnoses (p=۰.۰۲۵) were more frequent in Hispanics and they opted forchemotherapy more often (p=۰.۰۳۴); however, there were no significant differencesin outcomes and mortality among groups. When compared to the State tumorregistry, our population had more LCIS diagnoses (p=۰.۰۱), earlier stages (I p=۰.۰۲;II p=۰.۰۰۶), received more treatment overall (radiation p=۰.۰۲, chemotherapyp=۰.۰۰۰۱) and experienced better survival (p=۰.۰۰۴). In comparing the studypopulation to the SEER database, higher rates of LCIS and IDC and lower rates ofILC and mixed histology in the study population were noted. LCIS and IDC weremore prevalent in our cohort than SEER data (p=۰.۰۰۵, p=۰.۰۵, respectively),although we noted less ILC and mixed histology (p=۰.۰۳ and p=۰.۰۴).Conclusion: These data are the first reported for Hispanics in our state andhighlight the need for larger studies to better serve this growing demographic.