Spindle Cell Carcinoma of the Breast: A Case Report Representing Diagnostics, Therapeutics, Intervention, and Outcome
محل انتشار: فصلنامه سرطان پستان، دوره: 8، شماره: 4
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 155
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شناسه ملی سند علمی:
JR_ARCHB-8-4_014
تاریخ نمایه سازی: 9 آبان 1401
چکیده مقاله:
Background: Spindle cell carcinoma (SpCC) is an unusual form of squamous cell carcinoma (SCC) and can sometimes present in the breast. Owing to the rarity of breast SpCC, few case studies are available nowadays and proper evidence is scarce.Case presentation: We herein report a ۶۰-year-old female patient, who was referred to the surgery services after presenting with a right breast ulcerated mass. On physical examination, a ۷x۷cm mass was found along with a ۳cm ulcer on the top of it. Both mammography and ultrasound showed a dense mass, and tru-cut and skin punch biopsies confirmed neoplastic spindle cells within the lesion. The patient underwent a right total mastectomy with sentinel lymph node biopsies with no further chemotherapy or radiotherapy.Conclusion: Owing to the heterogeneity of SpCC, there is no exact treatment protocol for this type of cancer, and mastectomy or conservative surgery can be performed in certain groups of patients depending on tumor size, stage, and lymph node involvement. Fortunately, promising medical and biological therapies might be of use in the near future.
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نویسندگان
Mohammad Naser Athomnah
Department of General Surgery, Princess Basma Teaching Hospital, Irbid, Jordan
Shatha M Al-Barrak
Department of Acute Medicine, Ninewells Hospital, NHS Tayside, Scotland
Nimah A.Rabai
Department of General Surgery, Princess Basma Teaching Hospital, Irbid, Jordan
Tea Natelauri
Clinical Oncology Department, EVEX Hospitals, Georgia
Hussein S O AI Azzam
Department of General Surgery, Princess Basma Teaching Hospital, Irbid, Jordan
Mohammed Alorjani
Department of Pathology and Microbiology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan