Relationship between prostate cancer and sexual activity: A casecontrol study

Background: Prostate cancer is the fourth most prevalent cancer in the world with bothenvironmental and genetic risk factors. Recently, the role of sexual activity (in terms of periodand frequency) has been considered as a possible risk factor.Methods: A total of ۱۲۰ patients participated in the present case-control study, ۵۹ withprostate cancer and ۶۱ with other urologic conditions, in Shahid Beheshti Hospital of Hamadan,Iran, in ۲۰۱۶. A researcher-designed questionnaire was used to collect required informationsuch as participants' sexual habits. Finally, data were analyzed using SPSS software ۱۶ (SPSSInc., Chicago, IL, USA).Results: Mean sexual activity (per week) for the past ۵-۱۰ years was ۱.۸±۱.۰۲ and ۱.۶±۰.۲۲in case and control group, respectively (P=۰.۲). Mean sexual activity (per week) one year priorto diagnosis of the disease was also ۱.۳±۱.۱۰ and ۱.۱±۱.۰۳ in cases versus in the controls(P=۰.۴۵). In ۷۱-۸۰ years and >۸۰ years age group, sexual activity (days per week) in ۵-۱۰ yearsbefore diagnosis was significantly higher in cases compared with in control group (P=۰.۰۰۵and P=۰.۰۳, respectively). In <۶۰ years age group, participants' sexual activity in ۵-۱۰ yearsbefore diagnosis was significantly higher in controls as compared with case group (P=۰.۰۳).Also, sexual activity (days per week) at age ۷۱-۸۰ years in one year before diagnosis wassignificantly higher in case group compared with that of the control group (P=۰.۰۰۱).Conclusion: According to the results, it seems there is no clear relationship between sexualactivity and prostate cancer, but the results indicated different impacts of sexual activity indifferent ages in patients with prostate cancer.