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مقالات فارسیISIکنفرانسهاژورنالها

Toxicological Effects on Selected Tissues of Rats Fed Glycoalkaloid-Rich and Light-Exposed Solanum Tuberosum

محل انتشار: فصلنامه تغذیه و امنیت غذایی، دوره: 7، شماره: 4
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 94

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لینک ثابت به این مقاله:
https://civilica.com/doc/1551804

شناسه ملی سند علمی:

JR_JNFS-7-4_011

تاریخ نمایه سازی: 21 آبان 1401

چکیده مقاله:

Background: Exposure of potato tubers to light causes accumulation of glycioalkaloids in the tubers and overdose of glycoalkaoids are associated with some toxicity. This study aims to investigate the effect of consuming sunlight exposed tubers of Irish potato on some selected tissues of rats. Methods: Freshly harvested tubers of Solnum tuberosum were purchased from a farmland and were randomly grouped into five groups. Groups ۱- ۴ consisted of tubers exposed to sunlight (including visible and invisible light e.g. ultraviolet) for a period of ۱, ۲, ۳, and ۴ week(s), respectively, while group ۵ served as the control and consisted of freshly harvested tubers of Irish potato that have not been exposed to sunlight. The glycoalkaloids content was determined in both the non-exposed (control) and sunlight exposed tubers. Thereafter the tubers were formulated as diet and administered to rats. Biochemical analyses on serum lipid profile, enzymes of selected tissues (serum, liver, and kidney) and lipid peroxidation were carried out. Results: The results showed that the total glycoalkaloids content of the exposed sunlight groups (۲۳۰, ۲۵۰, ۲۷۰, and ۳۰۰ mg/kg fresh weight, respectively) significantly increased compared to the control group (۱۰۰ mg/kg fresh weight). A significant reduction (P < ۰.۰۵) in activities of alanine aminotransferase, aspartate aminotransferase and a significant upsurge (P < ۰.۰۵) in alkaline phosphatase activity was observed in the selected tissues of sunlight-exposed potato tuber animal groups compared to the (non-exposed) group. Lipid peroxidation assessment revealed a significant upsurge (P < ۰.۰۵) in malondialdehyde formation and a mild alteration in serum lipid profile. Conclusion: The study concluded that consumption of sunlight exposed Solanum tuberosum tubers may pose a threat on vital organs of the body irrespective of duration of exposure.

کلیدواژه ها:

Solanum tuberosum ، Glycoalkaloids ، Alanine aminotransferase ، Aspartate aminotransferase ، Lipid peroxidation

نویسندگان

Ayodeji Oluwafemi Idowu

Department of Biochemistry, College of Basic Medical Sciences, Federal University of Health Sciences, Otukpo, Benue State, Nigeria

Aduke Oluremi Saliu

Department of Environmental Health Science, School of Health Sciences, National Open University of Nigeria (NOUN), Abuja, Nigeria

Babamotemi Oluwasola Itakorode

Department of Biochemistry, College of Basic Medical Sciences, Federal University of Health Sciences, Otukpo, Benue State, Nigeria

Cecilia Nireti Fakorede

Department of Microbiology, College of Natural and Applied Sciences, Oduduwa University, P.M.B. ۵۵۳۳, Ile-Ife, Osun State, Nigeria

Rotimi Olusanya Arise

Department of Biochemistry, School of Life Sciences, University of Ilorin, P.M.B ۱۵۱۵, Ilorin, Kwara State, Nigeria

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  • Adeyeye SA & Akingbala JO ۲۰۱۴. Evaluation of nutritional and ...
  • Ahmed Z & King E ۱۹۶۰. Kinetics of placental alkaline ...
  • Akanji MA, Olagoke OA & Oloyede OB ۱۹۹۳. Effect of ...
  • Assmann G, Jabs H-U, Kohnert U, Nolte W & Schriewer ...
  • Association of Official Analytical Chemists ۲۰۰۰. The Association of Official ...
  • Beals KA ۲۰۱۹. Potatoes, nutrition and health. American journal of ...
  • Bushway A, Bushway R & Kim C ۱۹۸۸. Isolaton, partial ...
  • Butterworth P & Moss D ۱۹۶۶. Action of neuraminidase on ...
  • Dale M, Griffiths D, Bain H & Todd D ۱۹۹۳. ...
  • Edwards EJ, Saint RE & Cobb AH ۱۹۹۸. Is there ...
  • Freedman MR & Keast DR ۲۰۱۲. Potatoes, including French fries, ...
  • Friedewald WT, Levy RI & Fredrickson DS ۱۹۷۲. Estimation of ...
  • Friedman M ۲۰۱۵. Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced ...
  • Friedman M & Dao L ۱۹۹۲. Distribution of glycoalkaloids in ...
  • Friedman M & Levin CE ۲۰۰۹. Analysis and biological activities ...
  • Friedman M, McDonald GM & Filadelfi-Keszi M ۱۹۹۷. Potato glycoalkaloids: ...
  • Friedman M, Roitman JN & Kozukue N ۲۰۰۳. Glycoalkaloid and ...
  • Gee J, et al. ۱۹۹۶. Effects of saponins and glycoalkaloids ...
  • Gordon T, Castelli WP, Hjortland MC, Kannel WB & Dawber ...
  • Gregory P, Sinden SL, Osman SF, Tingey WM & Chessin ...
  • Grunenfelder LA, Knowles LO, Hiller LK & Knowles NR ۲۰۰۶. ...
  • Gultekin F, Ozturk M & Akdogan M ۲۰۰۰. The effect ...
  • Hylla S, et al. ۱۹۹۸. Effects of resistant starch on ...
  • Jadhav S & Salunkhe D ۱۹۷۵. Formation and control of ...
  • Jadhav S, Sharma RP & Salunkhe D ۱۹۸۱. Naturally occurring ...
  • Kasnak C & Artik N ۲۰۱۸. Change in some glycoalkaloids ...
  • Keukens EA, et al. ۱۹۹۶. Glycoalkaloids selectively permeabilize cholesterol containing ...
  • Keukens EA, et al. ۱۹۹۵. Molecular basis of glycoalkaloid induced ...
  • Kunitomo M ۲۰۰۷. Oxidative stress and atherosclerosis. Journal of the ...
  • Malomo S ۲۰۰۰. Toxicological implication of ceftriaxone administration in rats. ...
  • McGill CR, Kurilich AC & Davignon J ۲۰۱۳. The role ...
  • Mensinga TT, et al. ۲۰۰۵. Potato glycoalkaloids and adverse effects ...
  • Murniece I, et al. ۲۰۱۱. Nutritional composition of freshly harvested ...
  • Narayanan C, Joshi D & Mujumdar A ۱۹۸۴. Hypoglycemic action ...
  • Ngaha E, Akanji M & Madusolumuo M ۱۹۸۹. Studies on ...
  • Ogbu S & Okechukwu E ۲۰۰۱. The effect of storage ...
  • Oloyede O & Sunmonu T ۲۰۰۸. Decrease in activities of ...
  • Ostrý V, Ruprich J & Skarkova J ۲۰۱۰. Glycoalkaloids in ...
  • Percival G ۱۹۹۹. The influence of light upon glycoalkaloid and ...
  • Percival G, Dixon GR & Sword A ۱۹۹۶. Glycoalkaloid concentration ...
  • Philip D ۱۹۹۴. Plasma enzymes in diagnosis In Clinical Chemistry ...
  • Reitman S & Frankel S ۱۹۵۷. A colorimetric method for ...
  • Rymuza K, et al. ۲۰۲۰. The Effect of Light Exposures ...
  • Şengül M, Keleş F & Keleş M ۲۰۰۴. The effect ...
  • Sukrasno YMS & Kusmardiyani S ۲۰۱۴. Influence of Cooking Methods ...
  • Tanios S, Eyles A, Tegg R & Wilson C ۲۰۱۸. ...
  • Turner S & Molyneaux H ۲۰۰۴. Agricultural science, potato breeding ...
  • Varshney R & Kale R ۱۹۹۰. Effects of calmodulin antagonists ...
  • Wright PJ & Plummer DT ۱۹۷۴. The use of urinary ...
  • Wróblewski F & Ladue JS ۱۹۵۵. Lactic dehydrogenase activity in ...
  • Yakubu M, Akanji M & Salau I ۲۰۰۱. Protective effect ...
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