Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa

Background: Carvacrol is the main phenolic compound of Satureja and thyme. Carvacrol has antibacterial, antifungal, anti-inflammatory, and anti-cancer properties.Objectives: The aim of this study is determine the peptide-modified carvacrol’s antibacterial effects against Staphylococcus epidermidis and Pseudomonas aeruginosa.Methods: The peptide-modified carvacrol’s antibacterial activity against Staphylococcus epidermidis and Pseudomonas aeruginosa was investigated by disk diffusion and MIC method.Results: The effects of modified carvacrol by the disk diffusion method had growth inhibition diameters of ۲۵mm and ۲۰mm against Staphylococcus epidermidis and Pseudomonas aeruginosa, respectively. Also, MIC against Staphylococcus epidermidis and Pseudomonas aeruginosa was ۱µg/ml and ۰.۵۱µg/ml, respectively.Conclusion: The peptide-modified carvacrol has some antibacterial effects.