Age-Specific Reference Intervals for Routine Laboratory Biochemical Tests in The Iranian Adolescent Girls

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 213

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شناسه ملی سند علمی:

JR_JCTM-10-4_001

تاریخ نمایه سازی: 18 دی 1401

چکیده مقاله:

Introduction: For interpretation of the most common biochemical markers reference intervals (RIs) are widely considered and reported. Therefore, in this study, we aimed to determine age-specific RIs for some biochemical tests by removing and/or limiting critical gaps including sex, age group, geographical region, measurement device, and type of kits and reagents for routine laboratory biochemical variables in healthy adolescent girls aged ۱۲-۱۹ years.Materials and Methods:  In this cross-sectional study a total of ۱۰۲۶ adolescent girl was recruited. According to the study aim, the levels of serum for some routine biochemical tests were measured on a BT-۳۰۰۰ auto-analyzer. On the basis of the non-parametric rank method and by use of CLSI Ep۲۸-A۳ guidelines, we determined age-specific RIs, including confidence interval ۹۰%, under specific exclusion criteria.Results: Age partitioning was required for none of the upper and lower limits of biochemical markers. All Serum biochemical tests concentration remained relatively constant throughout the age range. Conclusion: By removing and/or limiting critical gaps involved in reference values of biochemical tests, it has provided an important understanding of metabolic processes and it has facilitated clinical application to track different diseases better

نویسندگان

Mehran Pashirzad

Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Hamideh Ghazizadeh

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohsen Seddigh Shamsi

Department of Internal Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mahdiyeh Yaghooti-Khorasani

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Reza Assaran Darban

Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

Atieh Kamel Khodabandeh

Social Determinants of Health Research Center, Mashhad University of Medical sciences, Mashhad, Iran.

Ensieh Akbarpour Bahre

Social Determinants of Health Research Center, Mashhad University of Medical sciences, Mashhad, Iran.

Maryam Mohammadi Bajgiran

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Amin Mansouri

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Reza Javid Dash Bayyaz

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Parisa Asadian

Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

Khashayar Khanizadeh

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Hale Akhtari

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Melika Hadizadeh

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Arvin Babaei

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Sayyed Saeid Khayatzadeh

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Gordon A. Ferns

Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN۱ ۹PH, UK.

Habibollah Esmaily

Social Determinants of Health Research Center, Mashhad University of Medical sciences, Mashhad, Iran.

Majid Ghayour-Mobarhan

InInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

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