The Relationship between Clinical and Pathologic Findings in Patients with Upper GI Disorder: A Retrospective Descriptive Study

Background: The upper gastrointestinal tract disorder is common in different countries. Clinical signs are not specific. Therefore, correct diagnosis of abnormalities can be effective in appropriate treatment. The aim of this study is to determine the relationship between clinical findings, endoscopy and pathology in adult patients with upper gastrointestinal symptoms referring to the endoscopic ward of Shahid Sadoughi Hospital in Yazd, Iran during ۲۰۱۷-۲۰۲۲ in comparison with pediatric group. Methods: This study is a retrospective descriptive investigation. The study population includes patients with upper gastrointestinal symptoms who underwent endoscopy. The biopsy sample has been reported by the pathologist and results have been compared. Results: Totally, ۱۳۳۰ patients, (۱۱۲۰ adults and ۲۱۰ children) were enrolled in this study. There was no significant relationship between pathology findings of esophagus and clinical symptoms in children, but this association was significant in the stomach and duodenum. In adults, the relationship between clinical findings and pathology in the esophagus, stomach and duodenum was significant. Conclusion: According to the present study, we can conclude that endoscopic data alone cannot be used to diagnose upper gastrointestinal diseases. Pathological parameters are fundamental in addition to complementary information with the results of endoscopy