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مقالات فارسیISIکنفرانسهاژورنالها

Anti-inflammatory, immunomodulatory and anti-oxidant effects of Ocimum basilicum L. and its main constituents: A review

محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 26، شماره: 6
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 128

فایل این مقاله در 11 صفحه با فرمت PDF قابل دریافت می باشد

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لینک ثابت به این مقاله:
https://civilica.com/doc/1650692

شناسه ملی سند علمی:

JR_IJBMS-26-6_002

تاریخ نمایه سازی: 21 اردیبهشت 1402

چکیده مقاله:

Ocimum basilicum L. (O. basilicum) is an ornamental and therapeutic plant with various pharmacological effects and medical applications. In this article, detailed information on the anti-oxidant, immunomodulatory, and anti-inflammatory properties of O. basilicum and its main constituents was provided. The literature survey of the different databases until the end of November ۲۰۲۱ was explored on the immunomodulatory, anti-inflammatory and anti-oxidant effects of the herb and its constituents. The plant and its constituents showed diverse pharmacological effects including immunomodulatory, anti-inflammatory and anti-oxidant properties by improving of the inflammatory mediators including interleukin (IL)-۱۰, IL-۴, tumor necrosis factor-alpha (TNF-α), interferon gamma (IFN-γ), nitric oxide (NO), serum levels of IFN-γ, IL۱۰ and IL-۴, IgG, IgM and phospholipase A۲ (PLA۲), immunoglobulin E (IgE), total protein (TP), oxidant and anti-oxidant markers. O. basilicum and its main constituents therefore, could be effective on the treatment of diseases associated with inflammation, immune dysregulation and oxidative stress. The present review article provides readers with organized information about the anti-oxidant, immunomodulatory, and anti-inflammatory properties of O. basilicum.

کلیدواژه ها:

Anti-Oxidants ، Basil extract ، Inflammation ، Immunomodulation ، Ocimum basilicum

نویسندگان

Elaheh Kamelnia

Department of Biology, Faculty of Science, Science and Research Branch, Islamic Azad University, Tehran, Iran

Reza Mohebbati

Department of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran

Reyhane Kamelnia

Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran

Hesham El-Seedi

Pharmacognosy Group, Department of Pharmaceutical Biosciences, Biomedical Centre, Uppsala University, Uppsala, Sweden

Mohammad Hossein Boskabady

Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

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  • Osei Akoto C, Acheampong A, Boakye YD, Naazo AA, Adomah ...
  • Boskabady MH, Alitaneh S, Alavinezhad A. Carum copticum L.: A ...
  • Boskabadi J, Saadat S, Boskabady MH. The relaxant effect of ...
  • Kunwar RM, Mahat L, Acharya RP, Bussmann RW. Medicinal plants, ...
  • Kumar S, Bajwa B, Kuldeep S, Kalia A. Anti-inflammatory activity ...
  • Rokaya MB, Münzbergová Z, Timsina B. Ethnobotanical study of medicinal ...
  • Boskabady MH, Keyhanmanesh R, Khamneh S, Ebrahimi MA. The effect ...
  • Shakeri F, Boskabady MH. A review of the relaxant effect ...
  • Eftekhar N, Moghimi A, Roshan NM, Saadat S, Boskabady MH. ...
  • Shakeri F, Hosseini M, Ghorbani A. Neuropharmacological effects of Ocimum ...
  • Hozayen WG, El-Desouky MA, Soliman HA, Ahmed RR, Khaliefa AK. ...
  • Srivastava S, Cahill DM, Conlan XA, Adholeya A. A novel ...
  • Al Abbasy DW, Pathare N, Al-Sabahi JN, Khan SA. Chemical ...
  • da Silva Moura EdS, D’Antonino Faroni LR, Fernandes Heleno FF, ...
  • Purushothaman B, Prasanna Srinivasan R, Suganthi P, Ranganathan B, Gimbun ...
  • Pirtarighat S, Ghannadnia M, Baghshahi S. Biosynthesis of silver nanoparticles ...
  • Yahfoufi N, Alsadi N, Jambi M, Matar C. The immunomodulatory ...
  • Verma RS, Padalia RC, Chauhan A, Thul ST. Exploring compositional ...
  • Padalia RC, Verma RS, Chauhan A. Analyses of organ specific ...
  • Radulović NS, Blagojević PD, Miltojević AB. α‐Linalool–a marker compound of ...
  • Fitsiou E, Mitropoulou G, Spyridopoulou K, Tiptiri-Kourpeti A, Vamvakias M, ...
  • Zamfirache M-M, Padurariu C, Burzo I, Olteanu Z, Boz I, ...
  • Tsimogiannis D, Oreopoulou V. Classification of phenolic compounds in plants. ...
  • Tsao R. Chemistry and biochemistry of dietary polyphenols. Nutrients ۲۰۱۰;۲: ...
  • Sahin H, Turumtay EA, Yildiz O, Kolayli S. Grayanotoxin-III detection ...
  • Daniel V, Daniang I, Nimyel N. Phytochemical analysis and mineral ...
  • Khare CP. Indian medicinal plants: an illustrated dictionary: Springer Science ...
  • Bihari CG, Behera M, Kumar JP, Kumar TS. Pharmacognostical and ...
  • Razavi SM, Mortazavi SA, Matia‐Merino L, Hosseini‐Parvar SH, Motamedzadegan A, ...
  • Shakeri F, Eftekhar N, Roshan NM, Rezaee R, Moghimi A, ...
  • Boskabady MH, Jalali S. Effect of carvacrol on tracheal responsiveness, ...
  • Rodrigues LB, Martins AOBPB, Ribeiro-Filho J, Cesário FRAS, e Castro ...
  • Złotek U, Szymanowska U, Karaś M, Świeca M. Anti-oxidative and ...
  • Bae AH, Kim G, Seol GH, Lee SB, Lee JM, ...
  • Takeuchi H, Takahashi-Muto C, Nagase M, Kassai M, Tanaka-Yachi R, ...
  • Eftekhar N, Moghimi A, Hossein Boskabady M, Kaveh M, Shakeri ...
  • Rodrigues LB, Martins AOBPB, Cesário FRAS, e Castro FF, de ...
  • Selvakkumar C, Gayathri B, Vinaykumar KS, Lakshmi BS, Balakrishnan A. ...
  • Wibisono PAP. Utilization of basil leaves (Ocimum basilicum) and avocado ...
  • Saeidi F, Sajjadi SE, Minaiyan M. Antiinflammatory effect of Ocimum ...
  • Li H, Ge Y, Luo Z, Zhou Y, Zhang X, ...
  • Ingram S, Diotallevi M. Reactive oxygen species: Rapid fire in ...
  • Güez CM, Souza ROd, Fischer P, Leão MFdM, Duarte JA, ...
  • Shakeri F, Boskabady MH. Anti‐inflammatory, anti-oxidant, and immunomodulatory effects of ...
  • Ahmed AF, Attia FA, Liu Z, Li C, Wei J, ...
  • Mohebbati R, Hosseini M, Haghshenas M, Nazariborun A, Beheshti F. ...
  • Yadav RD, Jain S, Alok S, Mahor A, Bharti JP, ...
  • Parhizgar S, Hosseinian S, Hadjzadeh MAR, Soukhtanloo M, Ebrahimzadeh A, ...
  • Mohebbati R, Khazdair MR, Hedayati M. Neuroprotective effects of medicinal ...
  • Khazdair MR, Mohebbati R, Karimi S, Abbasnezhad A, Haghshenas M. ...
  • Tewari D, Pandey HK, Sah AN, Meena H, Chander V, ...
  • Alkadi H. Ocimum basilicum: A candidate plant against aflatoxins production ...
  • Chai PW. Antibacterial and anti-oxidant activities of Cinnamon (Cinnamomum Zeylanicum), ...
  • Othman MS, Khaled AM, Al-Bagawi AH, Fareid MA, Ghany RA, ...
  • Nguyen VT, Nguyen NQ, Thi NQN, Thi CQN, Truc TT, ...
  • Eftekhar N, Moghimi A, Boskabady MH. The effects of Ocimum ...
  • Bravo E, Amrani S, Aziz M, Harnafi H, Napolitano M. ...
  • Khaki A, Khaki AA, Ezzatzadeh A, Hamidreza A. Effect of ...
  • Kaurinovic B, Popovic M, Vlaisavljevic S, Trivic S. Anti-oxidant capacity ...
  • James O, Eniola OJ, Nnacheta O. Comparative evaluation of anti-oxidant ...
  • Teofilović B, Tomas A, Martić N, Stilinović N, Popović M, ...
  • Soliman A, Rizk M, Shalaby M, Elkomy A. Mechanisms of ...
  • Fokou JBH, Pierre NJ, Gisele EL, Christian NC, Michel JDP, ...
  • Hussain AI, Anwar F, Sherazi STH, Przybylski R. Chemical composition, ...
  • Ahmed AS, Fanokh AKM, Mahdi MA. Phytochemical identification and anti-oxidant ...
  • Mohamed FH, Abd Elaziz NY. Impact of Ocimum basilicum leaves ...
  • Rashidian A, Roohi P, Mehrzadi S, Ghannadi AR, Minaiyan M. ...
  • Amrani S, Harnafi H, Gadi D, Mekhfi H, Legssyer A, ...
  • Miraj S, Kiani S. Study of pharmacological effect of Ocimum ...
  • Srivastava S, Adholeya A, Conlan XA, Cahill DM. Acidic potassium ...
  • Tavafi M, Ahmadvand H. Effect of rosmarinic acid on inhibition ...
  • Lee S-J, Umano K, Shibamoto T, Lee K-G. Identification of ...
  • Feng X, Xu W, Li Z, Song W, Ding J, ...
  • Keyhanmanesh R, Boskabady MH, Eslamizadeh MJ, Khamneh S, Ebrahimi MA. ...
  • Athari SS, Athari SM, Beyzay F, Movassaghi M, Mortaz E, ...
  • Boskabady MH, Keyhanmanesh R, Khamneh S, Ebrahimi MA. The effect ...
  • Boskabady MH, Jalali S, Yahyazadeh N, Boskabady M. Carvacrol attenuates ...
  • Shifren A, Witt C, Christie C, Castro M. Mechanisms of ...
  • Rapinski M, Liu R, Saleem A, Arnason JT, Cuerrier A. ...
  • Eftekhar N, Moghimi A, Roshan NM, Saadat S, Boskabady MH. ...
  • Okazaki K, Nakayama S, Kawazoe K, Takaishi Y. Antiaggregant effects ...
  • Yamasaki K, Nakano M, Kawahata T, Mori H, Otake t, ...
  • Alavinezhad A, Boskabady MH. Antiinflammatory, anti-oxidant, and immunological effects of ...
  • El-Ashram A, Afifi A, Sakr SF. Effect of basil oil ...
  • Tsai K, Lin B, Perng D, Wei J, Yu Y, ...
  • Gomez-Flores R, Verastegui-Rodriguez L, Quintanilla-Licea R, Tamez-Guerra P, Tamez-Guerra R, ...
  • Renzulli C, Galvano F, Pierdomenico L, Speroni E, Guerra M. ...
  • Dashputre NL, Naikwade NS. Preliminary immunomodulatory activity of aqueous and ...
  • Kathirvel P, Ravi S. Chemical composition of the essential oil ...
  • Stanojevic LP, Marjanovic-Balaban ZR, Kalaba VD, Stanojevic JS, Cvetkovic DJ, ...
  • Rezzoug M, Bakchiche B, Gherib A, Roberta A, Kilinçarslan Ö, ...
  • Kavoosi G, Amirghofran Z. Chemical composition, radical scavenging and anti-oxidant ...
  • Kumar A, Shukla R, Singh P, Prakash B, Dubey NK. ...
  • Tran TH, Nguyen HHH, Nguyen DC, Nguyen TQ, Tan H, ...
  • Mehdizadeh T, Hashemzadeh M, Nazarizadeh A, Neyriz-Naghadehi M, Tat M, ...
  • Chaaban SB, Hamdi SH, Mahjoubi K, Jemâa JMB. Composition and ...
  • Bobakulov K, Ozek G, Ozek T, Asilbekova DT, Abdullaev ND, ...
  • EL MOKHTARI K, EL BROUZI A, M’hammed E, TALBI M. ...
  • Elsherbiny EA, EL KHATEEB AY, Azzaz NA. Chemical composition and ...
  • Özcan M, Chalchat J-C. Essential oil composition of Ocimum basilicum ...
  • Sundararajan B, Moola AK, Vivek K, Kumari BR. Formulation of ...
  • Mota I, Sánchez-Sánchez J, Pedro LG, Sousa MJ. Composition variation ...
  • Kadan S, Saad B, Sasson Y, Zaid H. In vitro ...
  • Venancio AM, Onofre ASC, Lira AF, Alves PB, Blank AF, ...
  • Mousavi M, Zaiter A, Becker L, Modarressi A, Baudelaire E, ...
  • Aye A, Jeon Y-D, Lee J-H, Bang K-S, Jin J-S. ...
  • Noor ZI, Ahmed D, Rehman HM, Qamar MT, Froeyen M, ...
  • Eftekhar N, Moghimi A, Boskabady MH. Prophylactic effect of rosmarinic ...
  • Abd El-Ghffar EA, Al-Sayed E, Shehata SM, Eldahshan OA, Efferth ...
  • Zaveri M, Desai N, Movaliya V. Effect of Ocimum basilicum ...
  • Rameshrad M, Salehian R, Fathiazad F, Hamedeyazdan S, Garjani M, ...
  • Açıkgöz MA. Establishment of cell suspension cultures of Ocimum basilicum ...
  • Hamad GM, Darwish AM, Abu-Serie MM, El Sohaimy SA. Antimicrobial, ...
  • Baj T, Baryluk A, Sieniawska E. Application of mixture design ...
  • Bora KS, Arora S, Shri R. Role of Ocimum basilicum ...
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